About

NANDO (Nanbyo Disease Ontology) is an ontology designed to classify and systematize diseases covered under Japan’s "Designated Intractable Diseases" and "Specified Chronic Diseases of Children" programs. NANDO integrates domestic rare disease information and enhances standardization and interoperability with international rare disease databases. NANDO (Nanbyo Disease Ontology) is Japan's first comprehensive ontology of intractable and rare disease terminology, systematically organizing diseases covered under the Designated Intractable Disease System and the Pediatric Chronic Specific Disease System, as defined by the Ministry of Health, Labour and Welfare of Japan. The official version of NANDO was released in 2021, and it has been continuously updated to reflect revisions to these systems. By integrating Japan's intractable disease information and enhancing compatibility with international disease databases, NANDO aims to improve standardization and interoperability. As part of this effort, NANDO is interoperable with the international rare disease ontology, MONDO (Mondo Disease Ontology), enabling global data sharing on intractable diseases.
- Vocabulary list

Download & License

NANDO is provided under the Creative Commons Attribution 4.0 International License. The data can be freely used for various purposes, including research, education, and commercial use. When using the data, please credit it as "Nanbyo Disease Ontology (NANDO), DBCLS".

・List of NANDO Files

How to develop

NANDO is constructed based on the Designated Intractable Disease System and the Pediatric Chronic Specific Disease System, as defined by the Ministry of Health, Labour and Welfare of Japan. It systematically organizes diseases by extracting lower-level disease names, structuring them into hierarchical parent-child relationships, and formalizing them as an ontology. Additionally, nanbyo disease names have been translated into English, and mappings to Mondo have been established. NANDO also aligns with international disease databases such as Orphanet and MedGen. After review by clinical genetic specialists, the data is made available not only in ontology format but also in an Excel format to accommodate a wide range of use cases.

Summary statistics

Feature	Count
Total number of terms	2,800+
Database cross references	6,000+
Term definitions	1,300+
Synonyms	3,000+

Disclaimer

NanbyoData and NANDO strive to provide data in good faith, but do not verify the accuracy, clinical validity, or usefulness of the data. The Database Center for Life Science (DBCLS) bears no responsibility, either expressed or implied, for any actions taken by users using this data. DBCLS also bears no responsibility for any damages incurred due to changes, interruptions, or cessation of this service. Additionally, the terms of this disclaimer align with those outlined in the "Disclaimer" section of the Life Science Integrated Database Center's site policy.

Contact

For inquiries regarding NANDO, please contact us at:
nanbyodata@dbcls.rois.ac.jp